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Article

Whole genome sequencing of Caribbean Hispanic families with late‐onset Alzheimer's disease

13 Mar 2018

Abstract excerpt

Abstract Objective To identify rare causal variants underlying known loci that segregate with late‐onset Alzheimer's disease (LOAD) in multiplex families. Methods We analyzed whole genome sequences (WGS) from 351 members of 67 Caribbean Hispanic (CH) families from Dominican Republic and New York multiply affected by LOAD. Members of 67 CH and additional 47 Caucasian families underwent WGS as a part of the...

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PMID: 29688227
DOI: 10.1002/acn3.537

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