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Extended genome-wide association study employing the African Genome Resources Panel identifies novel susceptibility loci for Alzheimer’s Disease in individuals of African ancestry

2023-08-30

Abstract excerpt

<h4>ABSTRACT</h4> <h4>INTRODUCTION</h4> Despite a two-fold increased risk, individuals of African ancestry have been significantly underrepresented in Alzheimer’s Disease (AD) genomics efforts. <h4>METHODS</h4> GWAS of 2,903 AD cases and 6,265 cognitive controls of African ancestry. Within-dataset results were meta-analyzed, followed by gene-based and pathway analyses, and analysis of RNAseq and whole-genome seque...

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Literature Corpus work: 51589eab-467e-5ec8-9e87-4b287af3f04c
DOI: 10.1101/2023.08.29.23294774

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