Article

Chronic IL-6 overproduction induces a tolerogenic response in aged mice after peripheral nerve injury

2024-03-13

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Highlights/Main points</h4> Astrocyte-targeted IL-6 overproduction during aging increases basal microglial acivation in the facial nucleus. During aging, chronic IL-6 overproduction does not modify microglial response after peripheral nerve injury but increases T-lymphocyte infiltration. Chronic IL-6 overproduction in aged mice does not modify facial motor neuron survival after facial nerve...

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Literature Corpus work: 5b7c8e10-100b-5751-83ab-0ca4e96d0cbb
DOI: 10.1101/2024.03.13.584805

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