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Aging Microglia—Phenotypes, Functions and Implications for Age-Related Neurodegenerative Diseases

14 Jun 2017

Abstract excerpt

Aging of the central nervous system (CNS) is one of the major risk factors for the development of neurodegenerative pathologies such as Parkinson's disease (PD) and Alzheimer's disease (AD). The molecular mechanisms underlying the onset of AD and especially PD are not well understood. However, neuroinflammatory responses mediated by microglia as the resident immune cells of the CNS have been reported for both...

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PMID: 28659790
DOI: 10.3389/fnagi.2017.00194

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