Article

Diversity of Immunoglobulin Heavy Chain Repertoire in Patients With Rheumatoid Arthritis

2021-12-06

Abstract excerpt

<h4>Objectives: </h4> Rheumatoid Arthritis (RA) is associated with polymorphism in major histocompatibility complex class II genes and dysregulations of CD4 + T cells which cause abnormalities in immune repertoire (iR) expression and intracellular signaling. We monitored nucleotide sequence changes in iR of immunoglobulin heavy chain ( IGH ), particularly complementarity determining region 3 (CDR3) during the cour...

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Literature Corpus work: 5b79eb1f-a54d-54c2-bedc-99ce1d3ef943
DOI: 10.21203/rs.3.rs-1125791/v1

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