Article

B cell receptor repertoire analysis unveils dynamic antibody response and severity markers in COVID-19 patients

2022-03-25

Abstract excerpt

<h4>ABSTRACT</h4> Humoral and cell mediated immunity are critical against viral infections. The knowledge of composition, diversity, gene usage of the B cell repertoires helps in determining the immune response to SARS-CoV-2 infection. Examining B cell response provides insights on therapeutic antibodies, disease severity markers and aids in predicting vaccine response. We have analyzed public domain immunoglobul...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 03cbca0a-4a9a-5787-bf15-ec71ccad3660
DOI: 10.1101/2022.03.24.485649

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

B cell receptor repertoire analysis unveils dynamic antibody response and severity markers in COVID-19 patientsDOI 10.1101/2022.03.24.485649Read

Landscapes and dynamic diversifications of B-cell receptor repertoires in COVID-19 patientsSemantic proximity Read

Characterization of B-cell receptor clonality and immunoglobulin gene usage at multiple time points during active SARS-CoV-2 infectionSemantic proximity Read

Global characterization of B cell receptor repertoire in COVID-19 patients by single-cell V(D)J sequencingSemantic proximity Read

Comparative global B cell receptor repertoire difference induced by SARS-CoV-2 infection or vaccination via single-cell V(D)J sequencingSemantic proximity Read

Human B cell clonal expansion and convergent antibody responses to SARS-CoV-2Semantic proximity Read

T cell receptor repertoire signatures associated with COVID-19 severitySemantic proximity Read

Pandemic, epidemic, endemic: B cell repertoire analysis reveals unique anti-viral responses to SARS-CoV-2, Ebola and Respiratory Syncytial VirusSemantic proximity Read

Germline IGHV3-53-encoded RBD-targeting neutralizing antibodies are commonly present in the antibody repertoires of COVID-19 patientsSemantic proximity Read

Contrasting Effects of SARS-CoV-2 Vaccination vs. Infection on Antibody and TCR RepertoiresSemantic proximity Read

Machine learning identifies T cell receptor repertoire signatures associated with COVID-19 severitySemantic proximity Read

Rapid isolation and immune profiling of SARS-CoV-2 specific memory B cell in convalescent COVID-19 patients via LIBRA-seqSemantic proximity Read

Global patterns of antigen receptor repertoire disruption across adaptive immune compartments in COVID-19Semantic proximity Read