Article

The effect of mitogen-activated protein kinase phosphatase-2 (MKP-2) overexpression in prostate cancer cell function and its clinical prostate cancer progression

2013-01-01

Abstract excerpt

MAP kinase signals have been reported as a crucial cancer chemopreventive and chemotherapeutic target due to their involvement in tumour cell growth, proliferation, apoptosis and survival. They consist principally of extracellular signal-regulated kinase (ERK), c-jun NH2- terminal kinase (JNK) and p38 MAP kinase, which has been correlated with a more malignant phenotype in several tumour models and in vivo. A key...

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Literature Corpus work: 5b548ead-a281-5a65-916e-911e2f5214d7
DOI: 10.48730/kbs5-9x88

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