Article

Protein kinase D promotes prostate cancer cell bone metastasis by positively regulating Runx2 in a MEK/ERK1/2-dependent manner

2022-04-17

Abstract excerpt

Most cancer patients die because of tumor metastasis not due to tumors at the primary site. Prostate tumors in advance stages frequently metastasize to the bone, which is the main cause of death for the disease. The family of protein kinase D (PKD) has been implicated in prostate cancer development, however, its role in prostate cancer metastasis has not been investigated. In this study, we examined the contributi...

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Literature Corpus work: be8a13f6-05c4-5131-b868-0d04d4f458f0
DOI: 10.1101/2022.04.16.488551

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