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Article

Inhibition of PP2A activity confers a TRAIL-sensitive phenotype during malignant transformation.

Molecular cancer research : MCR - 1 Feb 2014

Yang Hongmei, Chen Xuanyu, Wang Xuegang, Li Yansheng, Chen Shaoyong, Qian Xiaohui, Wang Rong, Chen Li, Han Weiwei, Ruan Anming, Du Quansheng, Olumi Aria F, Zhang Xiaoping

Abstract excerpt

UNLABELLED: TRAIL is a promising anticancer agent because it induces apoptosis in the majority of human cancer cells but spares the normal cells. To determine the mechanistic nature of how normal cells acquire a TRAIL-sensitive phenotype during the process of malignant transformation, an experime...

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Identifiers

PMID: 24296757
DOI: 10.1158/1541-7786.MCR-13-0441

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24296757-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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