Article

The Role of HERG channel in the Secretion of Glucagon-Like Peptide-1 (GLP-1) from Murine Intestinal L-Cells

2023-03-01

Abstract excerpt

HERG ion channel is a member of the Voltage-gated potassium (Kv) channels. A reduction in HERG function reduces potassium efflux during repolarization. Previous research has shown that patients with long QT syndrome due to HERG mutations have increased secretion of the hormone glucagon-like peptide-1 (GLP-1). However, the role of HERG in GLP-1 secretion remains uncertain. Here we report that HERG is expressed in G...

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Literature Corpus work: 5b291c8e-acec-5d7f-9e85-4903263b3fa9
DOI: 10.1101/2023.02.28.530535

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