Article
High-throughput Interpretation of Killer-cell Immunoglobulin-like Receptor Short-read Sequencing Data with PING.
PLoS computational biology - 1 Aug 2021
Marin Wesley M, Dandekar Ravi, Augusto Danillo G, Yusufali Tasneem, Heyn Bianca, Hofmann Jan, Lange Vinzenz, Sauter Jürgen, Norman Paul J, Hollenbach Jill A
Abstract excerpt
The killer-cell immunoglobulin-like receptor (KIR) complex on chromosome 19 encodes receptors that modulate the activity of natural killer cells, and variation in these genes has been linked to infectious and autoimmune disease, as well as having bearing on pregnancy and transplant outcomes. The medical relevance and high variability of KIR genes makes short-read sequencing an attractive technology for...
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