Article

Loss of function in the autism and learning disabilities associated gene <i>Nf1</i> disrupts corticocortical and corticostriatal functional connectivity in human and mouse

2019-04-26

Abstract excerpt

<h4>ABSTRACT</h4> Children with the autosomal dominant single gene disorder, neurofibromatosis type 1 (NF1), display multiple structural and functional changes in the central nervous system, resulting in neuropsychological cognitive abnormalities. Here we assessed the pathological functional organization that may underlie the behavioral impairments in NF1 using resting-state functional connectivity MRI. Coherent...

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Literature Corpus work: 5ab4137a-2e41-5366-9454-b26aef11f0c5
DOI: 10.1101/618223

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