Article

Comprehensive mapping of Neurofibromin (NF1) expression in developing mouse brain

2026-03-24

Abstract excerpt

Neurofibromin (NF1) is a critical negative regulator of the RAS-RAF-ERK pathway, mutations in which have been clinically implicated in various neurodevelopmental disorders. However, the lack of a high-resolution spatiotemporal map has obscured the understanding of why specific cell populations and developmental processes are uniquely vulnerable to NF1 loss. In this study, we present a comprehensive atlas of NF1 e...

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Literature Corpus work: 15db8aaa-763f-5a76-9bc3-63b5052a2e83
DOI: 10.64898/2026.03.22.713444

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