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Article

Wnt and planar cell polarity signaling in cystic renal disease

25 Oct 2013

Abstract excerpt

Cystic kidney diseases can cause end stage renal disease, affecting millions of individuals worldwide. They may arise early or later in life, are characterized by a spectrum of symptoms and can be caused by diverse genetic defects. The primary cilium, a microtubule-based organelle that can serve as a signaling antenna, has been demonstrated to have a significant role in ensuring correct kidney development and...

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PMID: 24162855
DOI: 10.4161/org.26766

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