Article

Variant-specific spike conformational dynamics shape memory B cell selection during recall

2026-07-20

Abstract excerpt

<h4>ABSTRACT</h4> Immune imprinting profoundly shapes antibody responses to breakthrough infections and vaccination against evolving endemic viruses. Current vaccine design primarily focuses on antigen sequence and variant mutations but rarely consider the structural context in which these antigens are being recognized. In this study, we make use of the longitudinal analysis of memory B cell (MBC) responses in bo...

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Literature Corpus work: 59ed8f5a-dae0-5e2e-8042-2f6fa7ec7612
DOI: 10.64898/2026.07.18.739204

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