Article

Omicron BA.1 breakthrough infection drives long-term remodeling of the memory B cell repertoire in vaccinated individuals

2023-01-29

Abstract excerpt

<h4>Summary</h4> How infection by a viral variant showing antigenic drift impacts a preformed mature human memory B cell (MBC) repertoire remains an open question. Here, we studied the MBC response up to 6 months after Omicron BA.1 breakthrough infection in individuals previously vaccinated with three doses of mRNA vaccine. Longitudinal analysis, using single-cell multi-omics and functional analysis of monoclonal...

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Literature Corpus work: 3841c45e-c77c-5bc5-9cef-9fc2f556e796
DOI: 10.1101/2023.01.27.525575

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