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Article

Effects of Nanopore Charge Decorations on the Translocation Dynamics of DNA.

Biophysical journal - 17 Oct 2017

Jou Ining, Muthukumar Murugappan

Abstract excerpt

We have investigated the dynamics of single-stranded DNA as it translocates through charge-mutated protein nanopores. Translocation of DNA is a crucial step in nanopore-based sequencing platforms, where control over translocation speed remains one of the main challenges. Taking advantage of the interactions between negatively charged DNA and positively charged amino acid residues, the translocation speed of DNA...

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Identifiers

PMID: 29045861
DOI: 10.1016/j.bpj.2017.08.045
PMCID: PMC5647626

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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