Article

Directional anchor genes refine polygenic informed treatment selection in schizophrenia and bipolar disorder

2022-03-22

Abstract excerpt

Genetically informed drug development and repurposing is an attractive prospect for improving outcomes in patients with psychiatric illness; however, the effectiveness of these endeavours can be confounded by heterogeneity. In this study, we propose a novel approach that links interventions implicated by disorder-associated genetic risk, at the population level, to a framework that can target these compounds to in...

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Literature Corpus work: 59cdf98e-56c2-5659-87fd-2ae87c33b844
DOI: 10.1101/2022.03.20.22272666

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