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Article

Genetics-informed precision treatment formulation in schizophrenia and bipolar disorder.

American journal of human genetics - 1 Sept 2022

Reay William R, Geaghan Michael P, Atkins Joshua R, Carr Vaughan J, Green Melissa J, Cairns Murray J

Abstract excerpt

Genetically informed drug development and repurposing is an attractive prospect for improving patient outcomes in psychiatry; however, the effectiveness of these endeavors is confounded by heterogeneity. We propose an approach that links interventions implicated by disorder-associated genetic risk, at the population level, to a framework that can target these compounds to individuals. Specifically, results from...

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Identifiers

PMID: 36055211
DOI: 10.1016/j.ajhg.2022.07.011
PMCID: PMC9502060

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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