Article

Pathway and network-based strategies to translate genetic discoveries into effective therapies

2016-05-03

Abstract excerpt

<h4>ABSTRACT</h4> One way to design a drug is to attempt to phenocopy a genetic variant that is known to have the desired effect. In general, drugs that are supported by genetic associations progress further in the development pipeline. However, the number of associations that are candidates for development into drugs is limited because many associations are in noncoding regions or difficult to target genes. Appr...

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Literature Corpus work: 08cf9d85-d658-5bb8-a1cf-82d0201ec463
DOI: 10.1101/051524

Open publication

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