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Article

Genetic variation of pre-mRNA alternative splicing in human populations.

Wiley interdisciplinary reviews. RNA - 1 Jan 2000

Lu Zhi-Xiang, Jiang Peng, Xing Yi

Abstract excerpt

The precise splicing outcome of a transcribed gene is controlled by complex interactions between cis regulatory splicing signals and trans-acting regulators. In higher eukaryotes, alternative splicing is a prevalent mechanism for generating transcriptome and proteome diversity. Alternative splicing can modulate gene function, affect organismal phenotype and cause disease. Common genetic variation that affects...

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Identifiers

PMID: 22095823
DOI: 10.1002/wrna.120
PMCID: PMC3339278

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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