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Article

Identification of allele-specific alternative mRNA processing via transcriptome sequencing.

Nucleic acids research - 1 Jul 2012

Li Gang, Bahn Jae Hoon, Lee Jae-Hyung, Peng Guangdun, Chen Zugen, Nelson Stanley F, Xiao Xinshu

Abstract excerpt

Establishing the functional roles of genetic variants remains a significant challenge in the post-genomic era. Here, we present a method, allele-specific alternative mRNA processing (ASARP), to identify genetically influenced mRNA processing events using transcriptome sequencing (RNA-Seq) data. The method examines RNA-Seq data at both single-nucleotide and whole-gene/isoform levels to identify allele-specific...

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Identifiers

PMID: 22467206
DOI: 10.1093/nar/gks280
PMCID: PMC3401465

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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