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Discovery of a small peptide that increases yeast lifespan by enhancing the function of APC <sup>Cdh1</sup> in nondividing quiescent cells

2026-02-18

Abstract excerpt

<h4>ABSTRACT</h4> Aging is accompanied by molecular hallmarks conserved from yeast to humans. One such hallmark, senescence, is an irreversible nondividing state that promotes aging. We previously reported that mutants of the yeast Anaphase Promoting Complex (APC) shorten the lifespan of both dividing and nondividing cells. Here, we propose that activation of the APC will promote the maintenance of quiescent yeas...

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Literature Corpus work
5985756b-869f-5201-8035-c0389e32c2c3
DOI
10.64898/2026.02.17.706436
Open publication

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Discovery of a small peptide that increases yeast lifespan by enhancing the function of APC <sup>Cdh1</sup> in nondividing quiescent cellsDOI 10.64898/2026.02.17.706436
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