Article
Multi-kinase phosphorylation of the APC/C activator Cdh1 revealed by mass spectrometry.
Cell cycle (Georgetown, Tex.) - 1 Oct 2004
Hall Mark C, Warren Erin N, Borchers Christoph H
Abstract excerpt
Cdh1 contributes to proper exit from mitosis and maintenance of G(1) phase in eukaryotic cells by activating a large ubiquitin ligase called the anaphase-promoting complex, or cyclosome (APC/C). At the end of G(1), APC/C(Cdh1) is inhibited by cyclin-dependent kinase (CDK) phosphorylation of Cdh1....
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