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HLH-30/TFEB is necessary for chromatin reorganization and maintenance of cell quiescence during starvation in <i>C. elegans</i>

2025-11-03

Abstract excerpt

<h4>ABSTRACT</h4> Cellular quiescence is a metabolically active, non-proliferative state critical for tissue maintenance and regenerative capacity, with broad implications for aging and age-related diseases. In Caenorhabditis elegans , L1 developmental arrest upon hatching in the absence of food provides a robust in vivo model to study quiescence. Here, we investigate the roles of the transcription factors HLH-3...

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Literature Corpus work
e3712969-9719-5df4-bb43-5d81666f65e9
DOI
10.1101/2025.10.31.685810
Open publication

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HLH-30/TFEB is necessary for chromatin reorganization and maintenance of cell quiescence during starvation in <i>C. elegans</i>DOI 10.1101/2025.10.31.685810
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