Article

Identification of novel microcephaly-linked protein ABBA that mediates cortical progenitor cell division and corticogenesis through NEDD9-RhoA

2022-04-04

Abstract excerpt

The cerebral cortex, which is responsible for higher cognitive functions, relies on the coordinated asymmetric division cycles of polarized radial glial progenitor cells for proper development. Defects in the mitotic process of neuronal stem cells have been linked to the underlying causes of microcephaly; however, the exact mechanisms involved are not fully understood. In this study, we present a new discovery reg...

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Literature Corpus work: 596fa0af-40df-5a5e-9474-db0d3d89e08f
DOI: 10.1101/2022.03.28.22272122

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