Article

Hypertension-mediated cardiac fibrosis is a mechanical process initiated by smooth muscle cells

2026-08-10

Abstract excerpt

<title>Abstract</title> <p>Hypertension represents the most prevalent chronic cardiovascular condition, typically culminating in pathological cardiac remodeling characterized by hypertrophy and extensive fibrosis. Although the cellular phenotypes associated with these changes are well-documented, the precise mechanisms by which hypertensive stress is sensed and transduced into a fibrotic program remain poorly def...

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Literature Corpus work: 592799dd-5bd7-585b-82dc-838d28e3c330
DOI: 10.21203/rs.3.rs-10581981/v1

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