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Article

Linking LOXL2 to Cardiac Interstitial Fibrosis

17 Aug 2020

Abstract excerpt

Cardiovascular diseases (CVDs) are the leading causes of death worldwide. CVD pathophysiology is often characterized by increased stiffening of the heart muscle due to fibrosis, thus resulting in diminished cardiac function. Fibrosis can be caused by increased oxidative stress and inflammation, which is strongly linked to lifestyle and environmental factors such as diet, smoking, hyperglycemia, and hypertension....

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PMID: 32824630
DOI: 10.3390/ijms21165913

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