Article

Purification and biochemical analysis of native AMPA receptors from three different mammalian species

2022-09-16

Abstract excerpt

The majority of fast, excitatory synaptic transmission in the central nervous system (CNS) is mediated by α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs), which are glutamate-activated ion channels integral to synaptic plasticity, motor coordination, learning, and memory. AMPARs are multiprotein assemblies comprised of a tetrameric receptor core that co-assembles with a broad range of perip...

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Literature Corpus work: 58ebfed2-d6be-5b2e-903d-16e85390c906
DOI: 10.1101/2022.09.16.508249

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