Article

Hsp47 Promotes Biogenesis of Multi-subunit Neuroreceptors in the Endoplasmic Reticulum

2022-10-26

Abstract excerpt

<h4>ABSTRACT</h4> Protein homeostasis (proteostasis) deficiency is an important contributing factor to neurodegenerative, neurological, and metabolic diseases. However, how the proteostasis network orchestrates the folding and assembly of multi-subunit membrane proteins is not well understood. Previous proteomics studies identified Hsp47 (Gene: SERPINH1 ), a heat shock protein in the endoplasmic reticulum lumen,...

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Literature Corpus work: e1d834a7-310a-5a9b-892b-409f7eb6f114
DOI: 10.1101/2022.10.24.513629

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