Article

Quantitative interactome proteomics identifies proteostasis network for GABA <sub>A</sub> receptors

2022-03-08

Abstract excerpt

Gamma-aminobutyric acid type A (GABA A ) receptors, the primary inhibitory neurotransmitter-gated ion channels in the mammalian central nervous system, inhibit neuronal firing to preserve balanced neuronal activity. Maintenance of GABA A receptor protein homeostasis (proteostasis) in the cell utilizing its interacting proteins is essential for the function of GABA A receptors. However, how the proteostasis netw...

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Literature Corpus work: 0544ba5e-76f6-57d9-b8f2-d69eebe7004d
DOI: 10.1101/2022.03.08.483512

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