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Article

Contribution of the global subunit structure and stargazin on the maturation of AMPA receptors.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 17 Feb 2010

Shanks Natalie F, Maruo Tomohiko, Farina Anthony N, Ellisman Mark H, Nakagawa Terunaga

Abstract excerpt

Subunit assembly governs regulation of AMPA receptor (AMPA-R) synaptic delivery and determines biophysical parameters of the ion channel. However, little is known about the molecular pathways of this process. Here, we present single-particle EM three-dimensional structures of dimeric biosynthetic intermediates of the GluA2 subunit of AMPA-Rs. Consistent with the structures of intact tetramers, the N-terminal...

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Source

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Identifiers

PMID: 20164357
DOI: 10.1523/JNEUROSCI.5146-09.2010
PMCID: PMC2842908

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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