Article

Alternative splicing expands the antiviral IFITM repertoire in Chinese horseshoe bats

2023-12-04

Abstract excerpt

The interferon response is shaped by the evolutionary arms race between hosts and the pathogens they carry. The human interferon-induced transmembrane protein (IFITM) family consists of three antiviral IFITM genes that arose by gene duplication, they restrict virus entry and are key players of the interferon response. Yet, little is known about IFITMs in other mammals. Here, we identified an IFITM gene in Chines...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 58950dad-d8ff-5dff-9659-97fbd12b24b9
DOI: 10.1101/2023.12.04.569605

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Alternative splicing expands the antiviral IFITM repertoire in Chinese horseshoe batsDOI 10.1101/2023.12.04.569605Read

Alternative splicing expands the antiviral IFITM repertoire in Chinese rufous horseshoe batsSemantic proximity Read

Extraordinary diversity of antiviral immune-related gene families across 38 bat species.Semantic proximity Read

Identification of Fish Interferon Stimulated Genes and Their Antiviral MechanismsSemantic proximity Read

IRF7 in the Australian Black Flying Fox, Pteropus alecto: Evidence for a Unique Expression Pattern and Functional ConservationSemantic proximity Read

IFITM-Family Proteins: The Cell's First Line of Antiviral DefenseSemantic proximity Read

Interferon induced IFIT family genes in host antiviral defense.Semantic proximity Read

IFITM proteins: Understanding their diverse roles in viral infection, cancer, and immunitySemantic proximity Read

Comparison of antiviral responses in two bat species reveals conserved and divergent innate immune pathwaysSemantic proximity Read

Evolution of vertebrate interferon inducible transmembrane proteinsSemantic proximity Read

Bat-specific adaptations in interferon signaling and GBP1 contribute to enhanced viral toleranceSemantic proximity Read

IFITM Genes, Variants, and Their Roles in the Control and Pathogenesis of Viral InfectionsSemantic proximity Read

IFITM protein regulation and functions: Far beyond the fight against virusesSemantic proximity Read