Article
Extraordinary diversity of antiviral immune-related gene families across 38 bat species.
BMC biology - 9 Mar 2026
Liu Guangshuai, Ren Yingying, Zhou Shengyang, Hua Qinyang, Chen Peng, Zhang Honghai, Liu Zhen
Abstract excerpt
BACKGROUND: Despite harboring diverse pathogenic viruses, bats rarely exhibit clinical symptoms of the diseases. Previous research has reported evolutionary characteristics in key antiviral gene families in bats, such as natural killer cell receptors, MHC class I genes, and type I interferons, suggesting that bats may possess an immune tolerance that allows them to host viruses asymptomatically. However, this...
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