Article

Identification of Fish Interferon Stimulated Genes and Their Antiviral Mechanisms

2026-01-14

Abstract excerpt

The frontlines of innate antiviral immunity center on type I interferons (IFN), which are expressed by nearly all cell types as a cellular alarm signal. IFNs drive the expression of IFN-stimulated genes (ISGs), which can both generate an intracellular antiviral state and regulate the IFN response itself. This key antiviral line of defense is con-served in all jawed vertebrates, including teleost fish. Since their...

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Literature Corpus work: 42aea88a-17e2-50c7-aece-ee93fb7fbfae
DOI: 10.20944/preprints202601.0994.v1

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