Article

Asymmetrical cleavages of <i>Sleeping Beauty</i> transposons generate multiple excised transposon fragments during transposition

2019-06-03

Abstract excerpt

<h4>ABSTRACT</h4> Although the Sleeping Beauty (SB) transposon is the most validated DNA transposon used as a gene delivery vehicle in vertebrates, many details of the excision and integration steps in the transposition process are unclear. We have probed in detail the products of the excision step and apparent selective integration of a subset of those products during transposition. The standard model of SB tra...

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Literature Corpus work: 5877da0d-a2fc-5e78-ab09-2e99b324d9a6
DOI: 10.1101/659086

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