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Article

Our Conflict with Transposable Elements and Its Implications for Human Disease.

Annual review of pathology - 24 Jan 2020

Burns Kathleen H

Abstract excerpt

Our genome is a historic record of successive invasions of mobile genetic elements. Like other eukaryotes, we have evolved mechanisms to limit their propagation and minimize the functional impact of new insertions. Although these mechanisms are vitally important, they are imperfect, and a handful of retroelement families remain active in modern humans. This review introduces the intrinsic functions of...

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Identifiers

PMID: 31977294
DOI: 10.1146/annurev-pathmechdis-012419-032633

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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