Article

Sensory processing dysregulations as reliable translational biomarkers in <i>SYNGAP1</i> haploinsufficiency

2021-04-29

Abstract excerpt

Amongst the numerous genes associated with intellectual disability, SYNGAP1 stands out for its frequency and penetrance of loss-of-function variants found in patients, as well as the wide range of co-morbid disorders associated with its mutation. Most studies exploring the pathophysiological alterations caused by Syngap1 haploinsufficiency in mouse models have focused on cognitive problems and epilepsy, however...

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Literature Corpus work: c094807f-63cb-5ba0-aece-59489d9fa2b3
DOI: 10.1101/2021.04.28.441866

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