Article

Automated model building and protein identification in cryo-EM maps

2023-05-16

Abstract excerpt

Interpreting electron cryo-microscopy (cryo-EM) maps with atomic models requires high levels of expertise and labour-intensive manual intervention. We present ModelAngelo, a machine-learning approach for automated atomic model building in cryo-EM maps. By combining information from the cryo-EM map with information from protein sequence and structure in a single graph neural network, ModelAngelo builds atomic model...

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Literature Corpus work: 58034605-4f02-5195-a35e-867c79eae4e3
DOI: 10.1101/2023.05.16.541002

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