Article

End-to-end automation of repeat-target cryo-EM structure determination in CryoSPARC

2025-10-20

Abstract excerpt

Single particle cryo-EM is a valuable and growing technique for life science and drug discovery. Currently, obtaining state-of-the-art results from cryo-EM data analysis requires a human in the loop to analyze intermediate results and make image processing decisions. This bottleneck limits the achievable throughput of structure determination, especially in high-throughput settings such as structure-based drug desi...

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Literature Corpus work: 35951f20-31df-5bb1-aa0d-bde0032a9ca2
DOI: 10.1101/2025.10.17.682689

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