Article

Optimized path planning surpasses human efficiency in cryo-EM imaging

2022-06-17

Abstract excerpt

Cryo-electron microscopy (cryo-EM) represents a powerful technology for determining atomic models of biological macromolecules(Kühlbrandt, 2014). Despite this promise, human-guided cryo-EM data collection practices limit the impact of cryo-EM because of a path planning problem: cryo-EM datasets typically represent 2-5% of the total sample area. Here, we address this fundamental problem by formalizing cryo-EM data...

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Literature Corpus work: 3cf6d6a2-d707-5121-859e-85e063711797
DOI: 10.1101/2022.06.17.496614

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