Article

DNA2Graph enables automated identification of non-linear DNA molecules in electron microscopy

2026-08-06

Abstract excerpt

Electron microscopy of spread and rotary-shadowed DNA molecules provides a direct readout of DNA structure and remains uniquely informative for studying replication, recombination and repair intermediates. However, quantitative EM analysis is limited by the rarity of biologically informative structures and by the time required for expert operators to inspect very large numbers of molecules. Automated image acquisi...

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Literature Corpus work: 20f37eb4-9d0f-594f-9fa5-26bcf45d60cf
DOI: 10.64898/2026.08.05.742986

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