Article
Cancer, aging and the optimal tissue design.
Seminars in cancer biology - 1 Dec 2005
Komarova Natalia L
Abstract excerpt
Division patterns or mammalian tissues, like every other feature of life, have been subject to evolutionary pressures throughout the natural history. A particular and very important design principle that we discuss in this paper is the protective role of tissue architecture against cancer. We present a stochastic dynamical model of cell renewal of epithelial tissue (colonic crypts) which explicitly includes...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.