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Article

Examples of mathematical modeling: tales from the crypt.

Cell cycle (Georgetown, Tex.) - 1 Sept 2007

Johnston Matthew D, Edwards Carina M, Bodmer Walter F, Maini Philip K, Chapman S Jonathan

Abstract excerpt

Mathematical modeling is being increasingly recognized within the biomedical sciences as an important tool that can aid the understanding of biological systems. The heavily regulated cell renewal cycle in the colonic crypt provides a good example of how modeling can be used to find out key features of the system kinetics, and help to explain both the breakdown of homeostasis and the initiation of tumorigenesis....

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Identifiers

PMID: 17873520
DOI: 10.4161/cc.6.17.4649
PMCID: PMC2430384

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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