Article

MLL4 regulates postnatal palate growth and midpalatal suture development

2024-07-19

Abstract excerpt

MLL4, also known as KMT2D, is a histone methyltransferase that acts as an important epigenetic regulator in various organogenesis programs. Mutations in the MLL4 gene are the major cause of Kabuki syndrome, a human developmental disorder that involves craniofacial birth defects, including anomalies in the palate. This study aimed to investigate the role of MLL4 and the underlying mechanisms in the development and...

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Literature Corpus work: 5751f8bd-ec87-5bbf-9ab4-7ce5f948f4ce
DOI: 10.1101/2024.07.16.603832

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