Article
MicroRNA-124-3p suppresses mouse lip mesenchymal cell proliferation through the regulation of genes associated with cleft lip in the mouse.
BMC genomics - 14 Nov 2019
Suzuki Akiko, Yoshioka Hiroki, Summakia Dima, Desai Neha G, Jun Goo, Jia Peilin, Loose David S, Ogata Kenichi, Gajera Mona V, Zhao Zhongming, Iwata Junichi
Abstract excerpt
BACKGROUND: Cleft lip (CL), one of the most common congenital birth defects, shows considerable geographic and ethnic variation, with contribution of both genetic and environmental factors. Mouse genetic studies have identified several CL-associated genes. However, it remains elusive how these CL-associated genes are regulated and involved in CL. Environmental factors may regulate these genes at the...
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