Article
Identification of novel genes regulating the development of the palate.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Aug 2026
Bhaskar Ashwin, Astrof Sophie
Abstract excerpt
BACKGROUND: The International Mouse Phenotyping Consortium (IMPC) has generated thousands of knockout mouse lines, many of which exhibit embryonic or perinatal lethality. Using micro-computed tomography (micro-CT), the IMPC has created and publicly released three-dimensional image data sets of embryos from these lethal and subviable lines. In this study, we leveraged this data set to screen homozygous null...
Topics
- Animals
- Palate
- Mice
- Gene Expression Regulation, Developmental
- Cleft Palate
- Mice, Knockout
- X-Ray Microtomography
- Phenotype