Article

KMT2d regulates tooth enamel development

2024-08-21

Abstract excerpt

Amelogenesis, the process of enamel formation, is tightly regulated and essential for producing the tooth enamel that protects teeth from decay and wear. Disruptions in amelogenesis can result in amelogenesis imperfecta, a group of genetic conditions characterized by defective enamel, including enamel hypoplasia, marked by thin or underdeveloped enamel. Mutations in the KMT2D (MLL4) gene, which encodes a histone H...

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Literature Corpus work: 80c764e6-8d9e-5f51-8400-6afea16257eb
DOI: 10.1101/2024.08.20.608898

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