Article

Macrophages Promote Tumor Cell Extravasation across an Endothelial Barrier through Thin Membranous Connections

2023-02-16

Abstract excerpt

Macrophages are important players involved in the progression of breast cancer, including in seeding the metastatic niche. However, the mechanism by which macrophages in the lung parenchyma interact with tumor cells in the vasculature to promote tumor cell extravasation at metastatic sites is not clear. To mimic macrophage-driven tumor cell extravasation, we used an in vitro assay (eTEM) in which an endothelial m...

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Literature Corpus work: 5712ac41-c750-5dd9-9c17-51b187897c8f
DOI: 10.1101/2023.02.16.528161

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