Article

Hot-wiring clathrin-mediated endocytosis in human cells

2016-07-04

Abstract excerpt

Clathrin-mediated endocytosis (CME) is the major route of receptor internalization at the plasma membrane. Analysis of constitutive CME is complicated by the fact that initiation of endocytic events is unpredictable. When and where a clathrin-coated pit will form and what cargo it will contain are difficult to foresee. Here we describe a series of genetically encoded reporters that allow the initiation of CME on d...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 56f20ec1-9be3-5913-8815-4915a60cdb80
DOI: 10.1101/061986

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Hot-wiring clathrin-mediated endocytosis in human cellsDOI 10.1101/061986Read

Class-I myosin responds to changes in membrane tension during clathrin-mediated endocytosis in human induced pluripotent stem cellsSemantic proximity Read

Sterols lower energetic barriers of membrane bending and fission necessary for efficient clathrin mediated endocytosisSemantic proximity Read

Genome-edited human stem cells expressing fluorescently labeled endocytic markers allow quantitative analysis of clathrin-mediated endocytosis during differentiationSemantic proximity Read

Intrinsically disordered ligands for the control of receptor uptake by endocytosisSemantic proximity Read

Self-organizing actin networks drive sequential endocytic protein recruitment and vesicle release on synthetic lipid bilayersSemantic proximity Read

Contribution of the clathrin adaptor AP-1 subunit µ1 to acidic cluster protein sorting.Semantic proximity Read

Clathrin exchange during clathrin-mediated endocytosis.Semantic proximity Read

Principles of self-organization and load adaptation by the actin cytoskeleton during clathrin-mediated endocytosisSemantic proximity Read

In vivo monitoring of the recruitment and activation of AP-1 by Arf1.Semantic proximity Read

The contributions of the actin machinery to endocytic membrane bending and vesicle formation.Semantic proximity Read

CCDC32 stabilizes clathrin-coated pits and drives their invaginationSemantic proximity Read

A genetically encoded biosensor reveals location bias of opioid drug actionSemantic proximity Read